Cardiovascular Disease and COVID-19

This is the second part of a IH Blog series on Cardiovascular Disease.

By Brianna Koenick MPH (c) MMS (c) and Dr. Heather F. McClintock PhD MSPH MSW

More than 670 million people have been infected with COVID-19 worldwide. The pandemic exacerbated health disparities between high-income countries (HICs) and low-income and middle-income countries (LMICs), and the global community is continuing to grapple with the immediate and long-term implications of COVID-19. Long COVID is loosely defined as having symptoms at least two months after the initial infection and lasting for at least four weeks. A longitudinal cohort study conducted in South Africa found 39% of participants showed significant symptoms 6 months after a COVID-19 infection. In the United States, approximately 1 in 7 people have suffered from long COVID according to survey data. Cardiovascular disease (CVD) is a leading cause of death in the U.S. and globally, and substantial evidence suggests that the COVID-19 increases risk for poor cardiovascular outcomes. Researchers suggest that biological, social/psychological, and systemic factors underlie the complex relationship between CVD and COVID-19. Biologically, chronic inflammation and other physiological changes may contribute to increased CVD risk. Impaired social, behavioral and psychological well-being related to contextual influences related to the pandemic exacerbate CVD risk. Further, systemic breakdowns and infrastructure challenges lead to poor access to high quality care and services.

  Several systematic literature reviews and meta-analyses have documented a relationship between long COVID-19 and CVD. One of these investigations reviewed 150 studies focused on 57 cardiac complications published between January 2020 to July 2023 that persisted for at least 1 month after a COVID-19 infection. Their meta-analysis included 137 studies that identified 17 complications. They found a high prevalence of many complications, particularly chest pain and abnormal heart rhythms (arrhythmias). The authors noted that there were many CVD complications identified that lasted for years post COVID-19. The World Heart Federation has conducted “the largest global effort to reflect geographic spread” of COVID-19 and CVD aiming to determine the short-and long-term clinical sequelae among COVID-19 hospitalized patients across 16 low-middle-,upper-middle and high-income countries. Findings were presented at the 2023 European Society of Cardiology Conference indicating high post-discharge mortality for persons with COVID-19 in LMICs. Future predictions for CVD in the U.S. from 2025 to 2060 indicate that stroke will increase 33.8%, heart failure will increase 33.4%, ischemic heart disease will increase 30.7%, and heart attack will increase 16.9%. These CVD rate increases are expected to have the biggest impact on Black and Hispanic communities in the U.S. Globally, predictions indicate there will be a 50.2% increase in cardiovascular mortality rates between 2025 and 2050 with an increased burden on LMICs. 

Many initiatives and interventions have been implemented to try to reduce the CVD burden in the context of COVID-19. For instance, the U.S. Centers for Disease Control and Prevention developed the Community Health Workers for COVID Response and Resilient Communities initiative (CCR) to “strengthen the public health workforce, slow the spread of COVID-19, and move toward health equity.” Regarding long COVID, the NIH RECOVER Initiative was launched in 2021 and included the largest, most diverse study group to learn more about long COVID in hopes to treat and prevent it moving forward. The World Heart Federation has information and resources related to COVID-19 and CVD including those with practical applications for practicing professionals. While many effective and impactful projects have been implemented, further research and initiatives are needed to understand and address the complex relationship between CVD and COVID-19. 

Brianna Koenick MPH (c) MMS (c) 

Brianna Koenick is a current student in Arcadia University’s Dual Master of Public Health/Master of Medical Science in Physician Assistant Program. As an MPH student, her capstone research explored the relationship between lifestyle factors and cognitive health outcomes related to dementia. She completed an internship at the Jewish Relief Agency, a hunger-relief organization working to inspire volunteerism across the greater Philadelphia region, where she assisted the client services team with community outreach and developed communication materials for both clients and volunteers. Her public health interests include preventative health, environmental health, and health equity. After graduating, she plans to continue practicing evidence-based public health and advocating for the communities she will serve as a Physician Assistant.

Dr. Heather F. McClintock PhD MSPH MSW

Dr. McClintock is an IH Section Member and Associate Professor in the Department of Public Health, College of Health Sciences at Arcadia University. She earned her Master of Science in Public Health from the Department of Global Health and Population at the Harvard School of Public Health. Dr. McClintock received her PhD in Epidemiology from the University of Pennsylvania with a focus on health behavior and promotion. Her research broadly focuses on the prevention, treatment, and management of chronic disease and disability globally. Recent research aims to understand and reduce the burden of intimate partner violence in Sub-Saharan Africa. Prior to completing her doctorate she served as a Program Officer at the United States Committee for Refugees and Immigrants and a Senior Project Manager in the Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania. At the University of Pennsylvania she led several research initiatives that involved improving patient compliance and access to quality healthcare services including the Spectrum of Depression in Later Life Study and Integrating Management for Depression and Type 2 Diabetes Mellitus Study.

IH News Global Health Weekly News Round-Up

  • May 31 was observed as World anti-tobacco day by the World Health Organization.
  • The Fitness Industry Council Canada has announced June 1 as National Health and Fitness Day.

Politics and Policies:

  • The Republic of Congo has passed a law that prohibits the purchase, consumption and possession of tobacco for minors, pregnant women and mentally ill. The advising and any kind of promotion of tobacco are also prohibited in the country. Smoking is prohibited in public places.
  • According to the World Health Organization On June 10th Ethiopia is launching an emergency mass-vaccination campaign against yellow fever.
  • According to the Ghana’s Minister of Health, the country is committed to ban all forms of tobacco advertisements and promotions.
  • Smoking in presence of children equaled to physical violence in Latvia.
  • Russia’s smoking ban came into effect on Saturday. It involves no smoking in public places and curbing cigarette advertising and sales.

Programs:

  • The World Health Organization (WHO) in Gambia is launching polio campaign to vaccinate 400,000 children under five years.
  • The Ministry of Finance of Lesotho has signed two agreements totaling $17 million with the Global Fund to fight against HIV/AIDS, tuberculosis and malaria.
  • Professionals for Humanity International (PROFOH) have announced its third free medical screening in this year in Nigeria.
  • After the discovery of polio this week, United Nations emergency team rushes to vaccinate 424,000 people living in a refugee camp in Kenya.
  • Zimbabwe is going to conduct its first national tuberculosis prevalence survey with an objective to determine the national prevalence of bacteriologically-confirmed pulmonary TB among people aged 15 and over.
  • Rotary India extends its help to Pakistan in its polio vaccination drive.
  • The World Health Organization is calling on the countries to ban advertising about the tobacco products.

 Research:

  • Improvement of maternal health and reduction in child mortality in some countries was highlighted in a recently released report ‘Accountability for Maternal, newborn and Child Survival ‘.
  • According to the director of the National Institute of Combat of HIV (INLS), the prevalence of HIV in Angola has not changed since 1997.
  • According to the researchers patients who have developed oral cancer due to HPV can have sex with their spouses or long term partners.
  • According to a study done by the researchers at the Institute for Clinical Evaluative Sciences, rates of diabetes have jumped 15 fold within a decade for the Chinese Canadians.
  • A systemic review confirms that the licensed medicines for smoking cessation are successful in assisting people to quit smoking.
  • Scientists are using new optics-based single virus detecting methods for determining the exact viral load of a sample by counting individual virus sample.
  • New malaria vaccine developed by the team Japanese researchers has cut the infection rates by 72%.
  • A study conducted in over 13 hospitals in Indonesia, Singapore, Thailand and Vietnam shows that doubling Tamiflu vaccine dose does not help in severe flu.
  • Results of a study warn development of resistance to drug used in treatment of H7N9 virus.
  • A group of scientists discover how a single gene mutation helps brain cancer cells to survive and drive tumor growth.
  • According to the United Nations scientists, Fukushima No.1 nuclear plant has very low radiation doses and there is no increased risk of cancer on local residents.
  • According to the experts nearly one-sixth of young adults in Sri Lanka are overweight. Lack of nutrition education and food culture of the country are reasons for this problem.
  • A study states that particular combination of bacteria in the human digestive system can identify patients who have or are likely to develop Type 2 diabetes.
  • A study shows that the Coenzyme Q10 cuts the mortality rate by half in heart failure patients.
  • Report released by EU says that several new health risks are emerging from new chemicals, products and changing lifestyle patterns. It is important to address these issues all together.
  • According to a study fizzy drinks do harm to the teeth as drugs.
  • New vaccine for lung cancer has been developed by the scientists of Argentina and Cuba. It activates the body’s immune system to promote its destruction.

Diseases & Disasters:

  • Tornadoes hit Oklahoma again on 1st June. Death toll rises to 9.
  • A report issued by the Chinese Ministry of Land and Resources state that the ground water of China is poisoned. It did not address the severity and scope of this problem.
  • Death toll from bird flu has risen to 38 in China.
  • According to the reports of the United Nations, there is a suspected outbreak of Ebola fever in the north of the Democratic Republic of Congo.
  • According to the reports by Ghana Health Service, cholera outbreak hits greater Accra region.
  • The World Health Organization is concerned about the new strain of Coronavirus which has killed 55 of the confirmed cases.
  • A Starbucks in Hong Kong used water from the public restroom to brew coffee.
  • Pakistan is facing a severe measles epidemic. Since the start of 2013 about 239 deaths have been reported.
  • According to the Ministry of Health, Philippines, new cases of HIV infections recorded in the month of April were 388. It was 67 percent higher than those recorded in April 2012.
  • According to the reports Singapore is facing Dengue epidemic. More than 7,700 people are reported to be infected as of May 25.
  • Frozen berry and pomegranate mix has been reported to be linked to hepatitis A outbreak in five states in U.S.

IH News Global Health Weekly News Round-Up

  • First UN International Day of fistula marked in Ghana to ensure that victims were treated and re-integrated into society in Ghana.

Politics and Policies:

  • The government of Mauritius is preparing to enforce new laws for more graphic warnings on cigarette packs.
  • Voters in Portland have defeated measures to add fluoride to water supply.
  • The Texas House passed a measure that would prevent the state from expanding its Medicaid program.
  • Abortion Law (procedure at the 12th week of pregnancy) in Arkansas is temporarily blocked by a federal judge.

Programs:

  • The World Bank has announced $1 billion in a proposed new funding to help countries in the Africa’s Great Lakes Region to provide better health and education services besides targeting energy, roads, agriculture, cross-border trade and jobs.
  • United Nations Family Planning Innovation to launch two new initiatives that will increase access to family planning and improve maternal health in the world’s most marginalized areas.
  • The Business of a Better World (BSR) has launched an online platform to create culturally accurate training materials on women’s health in developing countries.
  • GlaxoSmithKline (GSK) has announced its contribution of $750,000 to the One Million Community Health Workers Campaign in sub-Sahara Africa.
  • Power to childcare centers ban unvaccinated children in Queensland.
  • An independent organization, Save the Children has received a contribution of $500,000 to support its ongoing flood relief efforts in Mozambique.
  • An emergency preparedness ad response center is being launched by the experts from the United Nations International Atomic Energy Agency (IAEA) in Fukushima, Japan.
  • United Nations refugee agency is working to help to contain cholera epidemic in Niger by implementing emergency sanitation and prevention measures.
  • UNICEF is working to prevent further spread of measles in the Central African Republic.
  • Mass vaccination campaign contained the spread of meningitis in South Sudan. The meningitis outbreak was declared by the ministry of health on April 30.

 Research:

  • According to the reports the World Health Organization has applauded Eritrea on its accomplishments in combating malaria.
  • Most EU beaches get clean bill of health, by the European Environment Agency. It says vast majority are clean and safe.
  • According to a new study relaxation of marijuana laws in Colorado has caused significant spike in number of young children treated for accidentally eating marijuana-laced cookies, candies, brownies and beverages.
  • A report by Substance Abuse and Mental Health Services Administration (SAMHSA) says that one in ten parents did not talk to their teen children about dangers of consuming drugs, alcohol etc.
  • In the 66th World Health Assembly, the WHO has praised Thailand for the world’s best governance for medicine.
  • According to the United Nations Report, the number of people in Africa receiving antiretroviral treatment has increased from less than 1 million to 7.1 million over the seven years.
  • According to a report released by the United Nations Japan must continue efforts to deactivate Fukushima nuclear plant.
  • In a report released by the United Nations greater efforts and more resources are needed to improve health of Palestinian refugees.
  • A study shows that potatoes and beans provide most nutrients per penny.
  • According to a study conducted by Dr. Bassiouny at Kornberg School of Dentistry, diet soda might be as bad for teeth health as taking methamphetamines or crack cocaine.
  • According to a study published in The Journal of Alzheimer’s Disease, two compounds found in cinnamon can play a role in delaying the onset of Alzheimer’s disease.
  • A research presented at the Heart Failure Congress 2013, heart failure accelerates the aging process and brings on early andropausal syndrome (AS).
  • The scientists at the Massachusetts Institute of Technology (MIT) have developed an injectable nanogel that can monitor blood-sugar levels and secrete insulin when treated.
  • A study revealed that the people who were interviewed while eating at fast food restaurants typically underestimate the calorie count of the meal in front of them by a large margin.

Diseases & Disasters:

  • A category EF-5 storm killed 24 people, injured many and damaged and estimated 12,000 homes in Moore, Oklahoma on May 20.
  • A parliamentary committee has revealed that since last year in Zimbabwe, more than 45,000 people have died due to HIV-related ailments and around 1.2 million people are living with this virus.
  • Disease kills children, causes miscarriages in camps near Nyala, South Darfur.
  • According to Tunisia Ministry of Health, SARS- like virus is being reported spreading among the people of country.

IH News Global Health Weekly News Round-Up

Politics and Policies:

  • Somalia signs its new Healthcare Plan. It has moved away from the emergency-level health provision towards more mainstream national health systems.
  • Kenya’s President elect promises much needed free primary healthcare for the citizens and raising the financing from 6-15%
  • Five memorandums of understandings has been signed by Egypt with South Sudan in the healthcare, livestock and agriculture sectors.
  • Tanzania and Japan sign Sh802 million project grant. It will help Tanzania in various sectors including health, education and water supply.
  • Kansas, United States, doctors may be required to tell patients that abortion causes breast cancer.

Programs:

  • The World Bank will help Cameroon to build safety net system aimed at reducing poverty and vulnerability. Households will get training to improve their health.
  • Solar power in Africa helps people to grow nutritional vegetables and improve their basic needs including health.
  • The United Nations Population Fund (UNFPA) calls for more reproductive health resources.
  • UNAIDS and other health organizations support new TB and HIV initiative in Africa.  It will include a package worth more than US$120 million to be used to expedite this process.
  • South Sudan through its community health workers detect and treat tuberculosis. This strategy is helping to fight tuberculosis draws communities themselves to detect and treat cases of tuberculosis.
  • UC San Francisco receives $2 million from billionaire Li K-shing for transforming its medical care by integrating data from the human genome and disease research with information from patient’s records and environmental data.

 Research:

  • According to a study about 570 United Kingdom children start smoking every day. This has made the UK government to consider whether to introduce plain packaging for tobacco products.
  • According to a study published in the New England Journal of Medicine physiotherapy results are as good as knee surgery.
  • According to a study, as part of prevention of mother-to-child transmission of HIV virus, antiretroviral therapy has to be initiated before the last trimester of pregnancy to achieve an undetectable RNA plasma viral load before delivery.
  • A report of United Nation states that about four and a half billion people have access to toilet (as compared to six billion people who have access to mobile phones) of the world’s seven billion people.
  • Researchers are working to tackle obstacles to medical aid.
  • According to the World Health Organization and Global Fund Africa and Europe has not yet reached the millennium tuberculosis goal. They say that strains of tuberculosis with resistance to multiple drugs could spread widely.
  • According to a report by the UNICEF, about 66 million Nigerians are without portable water.  It is the leading cause of diseases and deaths especially among under five aged children.
  • Doctors have discovered a women’s mysterious bone condition due to drinking a pitcher of tea every day for past 17 years.
  • Reports indicate that only 28% of Ugandans have access to hand-washing facilities. Statistics from the Uganda Demographic and Household Survey show that 190,000 Ugandan children die every year due to diarrhea.
  • A report publish by the World Health organization (WHO), among South-East Asia Region, Indonesia has achieved an amazing 90% success rate for TB treatment.
  • Scientists from the John Hopkins University have developed a new innovative method known as Predicting Infectious Disease Scalable Model (PRISM) extracts relationships between clinical, meteorological, climatic and socio-political data in Peru and the Philippines.
  • According to a study flu sufferers can spread the virus by sneezing, while talking, breathing by at least 6 feet.
  • A new method to treat blinding cornea diseases in children is now available in Singapore.
  • According to a study breast cancer radiation therapy increases a women’s risk of suffering a heart attack or other heart problems.
  • A study indicates an increase in the number of parents who won’t vaccinate daughters against Human Papilloma Virus (HPV).
  • A study shows that parents seem to be increasingly worried about the vaccine’s safety.
  • Low-GI protein blends have been designed to be eaten about 30 minutes before meals to reduce satiety is being marketed by a Swedish form Indevex. It increases release of incretin hormone which can provoke insulin release before blood glucose levels due to meal consumption.
  • A research done by Lund University in Sweden shows that we can modify the function of genes through epigenetic changes that can take place over the course of time.
  • United States tuberculosis rates reach all-time low but resistance of bacteria is a continuous threat.
  • Researchers have indicated that menstrual blood cells can be used to treat heart failure patients.
  • Researchers say that females with ovarian cancer too often get insufficient treatment.

Diseases and Disasters:

  • Chinese Public call for tackling water pollution.
  • Reports indicate that about 40 patients have lost their lives in drug trials in Maharashtra, India.
  • According to a report released by the CDC, from early December, 2012 to mid-February 2013, the Salmonella Typhimurium outbreak linked to ground beef had sickened a total of 22 people.
  • Natives of United States call for increased HIV testing per Centers for Disease Control and Prevention (CDC) recommendations.

IH News Global Health Weekly News Round-Up

Politics and Policies:

  • The government of United States is ready to enroll people in private health insurance plans starting this October 1.
  • Vermont state senate gives final approval those doctors will not face any criminal or civil liability when treating terminally ill patients who choose to end their lives.
  • The government of Uganda plans health insurance policy for the nation.

Programs:

  • With the aim of helping countries to make more informed health policy and program choices, World bank group has released a set of 22 case studies of countries that have significantly expanded access to health care in last decade.
  • Ghana launches television series to spark improvement in maternal health.
  • In order to improve health data collection by increasing access across the United States Government through the United States Agency for International Development (USAID) has handed over eight SUV to the Liberia Institute of Statistics and Geo-Information Services (LISGIS).
  • The Islamic Development Bank (IDB) provides $ 16 million loan to back up health sector in Mauritiana.
  • UNICEF seeks nearly US$7 million for tens of thousands of flood victims in Mozambique.
  • US$87 million has been approved by the World Bank to support climatic change resiliency and improvement of health and nutrition in Mozambique.
  • Carnegie Mellon University in Rwanda receives grant from Ricoh Innovations for eHealth research.
  • A two-day International Conference on Telemedicine for South –East Asian Countries has concluded with Adoption of Delhi Declaration in New Delhi.
  • Financial assistance of US$ 43,592 has been extended to the Kathmandu – based non-based government organization- the Nepal Diabetes Society.
  •  Sri Lanka gets US$200 million credit from World Bank to improve public health system.

Research:

  • According to a study, low levels of copper in brain may lead to senile beta amyloid deposition as senile plaques in brain in Alzheimer’s disease.
  • According to a study United States ranks low on health measures.
  • Scientists have discovered aromatic rice from Bangladesh that has very low arsenic content.  It is believed that its consumption will have major health benefits.
  • A study found that diabetes reduces sperm count and damages DNA in men.
  • According to the researchers work-related stress not related to cancers
  • Experts in their study state that even the young suffer from heart disease.
  • Researchers in their study have found a link between artificial sweeteners with obesity and type- 2 diabetes.
  • Study identifies regions of genes linked with Beh-ets’s disease.
  • According to a U.S. study of Israeli women in vitro fertilization  does not increase the risk of breast and gynecological cancer.
  • A study shows that Americans successfully manage diabetes.
  • A new study states that reducing salt in Americans diet would reduce death from stroke and heart attack.
  • A study in Norway states that folic acid supplements early in pregnancy may reduce risk of autism by 40%.
  • A study shows that people who eat chocolate frequently have a lower body mass index (BMI) that those who consume it less regulatory.
  • Study finds clues to why most babies in China survived tainted milk scandal.

Diseases & Disasters:

  • According to the Disease Control and Surveillance Unit of the Nkoranza South Municipal Health Directorate (Ghana), preventable communicable diseases have hit Nkoranza south municipality.
  • Acute drug shortage is being faced by the public schools of Malawi.
  • Cholera crisis confirmed in northern Mozambique after heavy rains and flooding.
  • Thousands of people are affected and hundreds killed in Hepatitis E outbreak in South Sudan refugee camps.
  • China checks levels of radiation in areas bordering North Korea. So far no signs of radiation in the region.
  • Number of people being affected with H1N1 virus is increasing in New Delhi, India.